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MGH and Harvard Medical School investigator Gary Ruvkun, PhD, has been named a recipient of the 2024 Nobel Prize in Physiology or Medicine for his role in the discovery of microRNA and its role in post-transcriptional gene regulation. He shares the award with his collaborator Victor Ambros, PhD, of the University of Massachusetts Medical School.
Over the past two decades, research into the potential of microRNAs for the diagnosis, prognosis and treatment of disease has expanded from the two original papers published by Ruvkun and Ambros in 1993 to 176,000 papers today.
Nobel Ceremony Video
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The Company of Biologists spoke to Margarete over Teams to learn more about her transition to becoming a group leader and her philosophy for creating a positive lab environment.
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Congratulations to Dr. Lee as she will continue to share her talents and expertise as Chair of the MGH Department of Molecular Biology, effective March 16, 2024.
Jeannie is a Member of the National Academy of Sciences, the National Academy of Medicine, a Harrington Rare Disease Scholar of the Harrington Discovery Institute, a recipient of the Lurie Prize from the Foundation for the National Institutes of Health, an awardee of the Centennial Prize from the Genetics Society of America, the 2010 Molecular Biology Prize and the 2020 Cozzarelli Prize from the National Academy of Sciences, U.S.A, and a Fellow of the American Association for the Advancement of Science. She has also served on the Board of the Genetics Society of America.
Clarivate Analytics’ Highly Cited Researchers List is an annual report of individuals at universities, research institutes and commercial organizations who demonstrate a significant and broad influence in their field or fields of research.The list focuses on contemporary research achievement: Only highly cited papers in the sciences and social sciences journals indexed in the Web of Science Core Collection™ during the 11-year period from 2011 to 2021 were surveyed. Highly cited papers are defined as those that rank in the top 1% by citations for field and publication year.
Press Release
Clarivate Analytics’ Highly Cited Researchers List is an annual report of individuals at universities, research institutes and commercial organizations who demonstrate a significant and broad influence in their field or fields of research.The list focuses on contemporary research achievement: Only highly cited papers in the sciences and social sciences journals indexed in the Web of Science Core Collection™ during the 11-year period from 2011 to 2021 were surveyed. Highly cited papers are defined as those that rank in the top 1% by citations for field and publication year. Please join us in congratulating the 52 researchers from Massachusetts General Hospital who were named to this year’s Highly Cited Researchers list!.
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The National Academy of Medicine (NAM) today announced the election of 90 regular members and 10 international members during its annual meeting. Election to the Academy is considered one of the highest honors in the fields of health and medicine and recognizes individuals who have demonstrated outstanding professional achievement and commitment to service. Jeannie was elected for research that has been central for understanding the roles of non-coding RNA in gene regulation. Using X-chromosome inactivation as a model, her investigations into extensive transcription of non-coding RNA are uncovering potential therapeutics to treat human diseases, including autism spectrum disorders, Rett Syndrome, and Fragile X Syndrome.
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The FNIH Awards 2023 Lurie Prize in Biomedical Sciences was awarded to Navdeep S. Chandel, Ph.D. and Vamsi Mootha, M.D.
Sneha P. Rath was announced as 1 out of 5 winners of the 2023 Lasker Foundation Essay Contest.
Novel Approach That Stimulates Cells’ DNA Repair Mechanisms May Combat a Leading Cause of Autism Spectrum Disorders
Featuring Jeannie T. Lee, MD, PhD and Hun-Goo Lee, PhD
Researchers have discovered that stimulating cells’ DNA repair mechanisms may correct the inherited genetic defect that defines fragile X syndrome, a leading cause of autism spectrum disorders. The method involves enhanced production of special nucleic acid structures called “R-loops” that cells see as DNA damage.
